To evaluate the effects of Zoletil (tiletamine- zolazepam) that have been widely used for the chemical testraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque (Macaca fuscata), this study was carried out.
Zoletil was administered by intramuscular injection. Evaluation of temperature, heart, rate, respiration rate and blood gas analysis were performed before administration and at 1, 10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded.
There was no significant difference in heart rate, PCO₂, PO₂after Zoletil administration but temperature, respiration rate, pH were significant difference compared with those of before administration. The induction time was 2.5±1.0min and maintenance time was 86±23.2min.
It was considered that Zoletil could be usefully used for the sedation and immobilization of Japanese macaque reared in Zoological garden.
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